Genetic Impact of a Butyrophilin-like 2 (BTNL2) Gene Variation on Specific IgE Responsiveness to Dermatophagoides farinae (Der f) in Japanese
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چکیده
منابع مشابه
Characterization of a novel allergen Der f 25, homologous to triose-phosphate isomerase, from Dermatophagoides farinae
Dermatophagoides farinae, as one species of house dust mites, was known to be rich in IgE-reactive components that contribute to allergy in China and worldwide. This study aims to characterize a novel allergen, the D. Farinae-derived Der f 25. In this study, total RNA was extracted from Dermatophagoides farinae and the full-length of Der f 25 gene was amplified by RT-PCR with the primers design...
متن کاملDermatophagoides farinae (Der f 1) and Dermatophagoides pteronyssinus (Der p 1) allergen exposure among subjects living in Uberlândia, Brazil.
BACKGROUND The role of mite allergen exposure in sensitization and development of asthma has been widely recognized. Previous studies have shown that Dermatophagoides pteronyssinus and Blomia tropicalis were the most prevalent house dust mites in Brazil, while D. farinae was rarely found. The aim of this study was to measure Der f 1 and Der p 1 allergen levels in Brazilian asthmatics' and contr...
متن کاملCrystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae
BACKGROUND Der f 7 is the group 7 allergen from the dust mite Dermatophagoides farinae, homologous to the major allergen Der p 7 from D. pteronyssinus. Monoclonal antibody that bind to residues Leu48 and Phe50 was found to inhibit IgE binding to residue Asp159, which is important for the cross-reactivity between Der f 7 and Der p 7. METHODOLOGY/PRINCIPAL FINDINGS Here, we report the crystal s...
متن کاملIn Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae
The house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. Der f 25 is a triosephosphate isomerase, representing the major allergen identified in Dermatophagoides farinae. The objective of this study was to predict the B and T cell epitopes of Der f 25. In the present study, we analyzed the physiochemical proper...
متن کاملCloning, bioinformatics analysis, and expression of the dust mite allergen Der f 5 of Dermatophagoides farinae
Crude extracts of house dust mites are used clinically for diagnosis and immunotherapy of allergic diseases, including bronchial asthma, perennial rhinitis, and atopic dermatitis. However, crude extracts are complexes with non-allergenic antigens and lack effective concentrations of important allergens, resulting in several side effects. Dermatophagoides farinae (Hughes; Acari: Pyroglyphidae) i...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2009
ISSN: 1323-8930
DOI: 10.2332/allergolint.08-oa-0005